Damiën Bierschenk

 

Damiën Bierschenk

 

PhD Candidate, Inflammasome Lab

 

 

Damiën obtained his Bachelor degree in life sciences in 2011 at the University of Applied Sciences in Rotterdam, the Netherlands. After receiving his degree he worked as a research assistant in the lab of Willem van Schaik at the University Medical Center Utrecht, the Netherlands. During this time Damiën co-authored various papers revolving around functional genomics of the gut pathogen Enterococcus faecium. He left the van Schaik lab to pursue a Masters degree in Biomedicine at the Karolinska institute in Stockholm, Sweden with a focus on immunology and microbiology. After receiving his Masters, Damiën joined the Inflammasome lab in October 2014 as a PhD candidate where he works on the activation of the inflammasome pathway by Salmonella.

 

The more difficult the victory, the greater the happiness in winning.

 

CONTACTS AND LINKS


 

Email: d.bierschenk@imb.uq.edu.au

Office Telephone: +61 7 3346 2356

Lab Telephone: +61 7 3346 2071

 

Institute for Molecular Bioscience

 

AWARDS AND PUBLICATIONS


 

 

AWARDS, GRANTS AND PRIZES

 

2014   International Postgraduate Research Scholarship, The University of Queensland

 

2014   Centennial Scholarship, The University of Queensland

 

EDUCATION

 

2014    Master in Biomedicine, Karolinska Institute, Stockholm, Sweden

 

2011    Bachelor in Life sciences, University of Applied Sciences, Rotterdam, The Netherlands

 

 

ORIGINAL RESEARCH ARTICLES

 

Baker PJ, Boucher D, Bierschenk D, Tebartz C, Whitney PG, D'Silva DB, Tanzer MC, Monteleone M, Robertson AA, Cooper MA, Alvarez-Diaz S, Herold MJ, Bedoui S, Schroder K, Masters SL (2015).
NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase-4 and caspase-5. European Journal of Immunology 45:2918-26. Pubmed
Comment in:
Potassium efflux fires the canon: Potassium efflux as a common trigger for canonical and noncanonical NLRP3 pathways. European Journal of Immunology

 

REVIEWS

 

Bierschenk D, Boucher D, Schroder K. (2016).
Salmonella-induced inflammasome activation in humans. Molecular Immunology S0161-5890(16)30242-5. Pubmed

 

Guzmán Prieto AM, Urbanus RT, Zhang X, Bierschenk D, Koekman CA, van Luit-Asbroek M, Ouwerkerk JP, Pape M, Paganelli FL, Wobser D, Huebner J, Hendrickx AP, Bonten MJ, Willems RJ, van Schaik W (2015).
The N-terminal domain of the thermo-regulated surface protein PrpA of Enterococcus faecium binds to fibrinogen, fibronectin and platelets. Sci Rep 5:18255.

 

Bollampalli VP, Harumi Yamashiro L, Feng X, Bierschenk D, Gao Y, Blom H, Henriques-Normark B, Nylén S, Rothfuchs AG (2015).
BCG Skin Infection Triggers IL-1R-MyD88-Dependent Migration of EpCAMlow CD11bhigh Skin Dendritic cells to Draining Lymph Node During CD4+ T-Cell Priming. PLoS Pathogens 11(10):e1005206.

 

Zhang X, Rogers M, Bierschenk D, Bonten MJ, Willems RJ, van Schaik W (2013).
A LacI-family regulator activates maltodextrin metabolism of Enterococcus faecium. PLoS One 8(8):e72285

 

Zhang X, Bierschenk D, Top J, Anastasiou I, Bonten MJ, Willems RJ, van Schaik W (2013).
Functional genomic analysis of bile salt resistance in Enterococcus faecium. BMC Genomics 14:299.

 

Zhang X, Top J, de Been M, Bierschenk D, Rogers M, Leendertse M, Bonten MJ, van der Poll T, Willems RJ, van Schaik W (2013).
Identification of a genetic determinant in clinical Enterococcus faecium strains that contributes to intestinal colonization during antibiotic treatment. J Infect Dis. 207(11):1780-6

 

Zhang X, Paganelli FL, Bierschenk D, Kuipers A, Bonten MJ, Willems RJ, van Schaik W (2012).
Genome-wide identification of ampicillin resistance determinants in Enterococcus faecium. PLoS Genetics 8(6):e1002804.

 

Spuesens EB, Meijer A, Bierschenk D, Hoogenboezem T, Donker GA, Hartwig NG, Koopmans MP, Vink C, van Rossum AM (2012).
Macrolide resistance determination and molecular typing of Mycoplasma pneumoniae in respiratory specimens collected between 1997 and 2008 in The Netherlands. J Clin Microbiol. 50(6):1999-2004.