Dr Amy Chan


Dr Amy Chan


Postdoctoral Researcher
Inflammasome Lab



After obtaining First Class Honours in 2014 in the Toth lab, Amy completed a year of voluntary research to explore her interests in the field of immunology. Working in collaboration with the Institute for Glycomics at Griffith University, she developed a novel prophylactic vaccine against streptococcus pyogenes. Amy joined the Inflammasome Lab in 2016 for her PhD studies. Her PhD project is unravelling the mysteries of the poorly understood “non-canonical” inflammasome.




Email: amy.chan@imb.uq.edu.au

Office Telephone: +61 7 3346 2071










2017-2020  Young Science Ambassador Award (Wonder of Science)

2019  Life Science Young Achiever Award (Women in Technology)

2018 & 2019  Tutor Excellence Award (UQ)

2018  People's Choice Award for QLD Women In STEM

2016  Australian Postgraduate Award

2014  Dean’s Commendation for Academic Excellence, The University of Queensland




2014  BSc Honours (Biochemistry), Supervisor: Professor Istvan Toth, The University of Queensland

2013  Bachelor of Science, The University of Queensland



Ross C, Chan AH, von Pein JB, Maddugoda MP, Boucher D, Schroder K (2022).
Inflammatory Caspases: Toward a Unified Model for Caspase Activation by Inflammasomes. Annual Review of Immunology Apr 26;40:249-269. Pubmed


Bonfim-Melo A, Noordstra I, Gupta S, Chan AH, Jones MJK, Schroder K, Yap AS (2022).
Rapid lamellipodial responses by neighbor cells drive epithelial sealing in response to pyroptotic cell death. Cell Reports Feb 1;38(5):110316. Pubmed


Chan AH, Schroder K (2020).
Inflammasome signaling and regulation of interleukin-1 family cytokines. Journal of Experimental Medicine Jan 6;217(1):e20190314. Pubmed


Ross C, Chan AH, Von Pein J, Boucher D, Schroder K (2018).
Dimerization and auto-processing induce caspase-11 protease activation within the non-canonical inflammasome. Life Science Alliance Dec 6;1(6):e201800237. Pubmed


Boucher D, Chan A, Ross C, Schroder K. (2018).
Quantifying Caspase-1 Activity in Murine Macrophages. Methods in Molecular Biology 1725:163-176. Pubmed



Chan A, Hussein WM, Ghaffar KA, Marasini N, Mostafa A, Eskandari S, Batzloff MR, Good MF, Skwarczynski M, & Toth I (2016).
Structure-activity relationship of lipid core peptide-based Group A Streptococcus vaccine candidates. Bioorganic & Medicinal Chemistry 24(14):3095-3101. Pubmed