Discovery

Major research discoveries, ususally linked to a high profile publication.

The Inflammasome Lab have discovered a new pathway for host defence against cytosolic Gram-negative bacteria, revealing unexpected links between pyroptosis and NETosis.

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The Inflammasome Lab have discovered a new pathway for host defence against cytosolic Gram-negative bacteria, revealing unexpected links between pyroptosis and NETosis.

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New research from Inflammasome Lab reveals trafficking mechanisms driving the unconventional secretion of mature interleukin-1β in non-pyroptotic and pyroptotic myeloid cells, and functions for caspase-1 and Gasdermin-D therein.

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The lab celebrated new paper acceptances with a pub crawl of Brisbane's finest establishments in West End on Friday. Congratulations to everyone in the Inflammasome Lab, and to our wonderful overseas collaborators!

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The Inflammasome Lab is thrilled to have our recent research featured in the Journal of Experimental Medicine special collection.  

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This month we farewell Damiën Bierschenk, who leaves the Inflammasome Lab for Sweden after submitting his PhD thesis.

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The Inflammasome Lab have discovered that neutrophils can signal via TNFR1-driven ripoptosome assembly to induce both cell death and IL-1β maturation, but suppress TLR4-dependent cell death and NLRP3 inflammasome activation during IAP inhibition,

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Inflammasome signalling animation

The Inflammasome Lab have uncovered precisely how caspase-1 is activated upon inflammasomes, which has revealed a new model for inflammasome signalling, function, and signal shutdown.

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The Inflammasome Lab have uncovered precisely how caspase-1 is activated upon inflammasomes, which has revealed a new model for inflammasome signalling, function, and signal shutdown.

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Inflammasome special issue

The inflammasome special issue of Journal of Molecular Biology, co-edited by Kate Schroder, Thirumala-Devi Kanneganti, Feng Shao and Petr Broz, is now online.

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